爱上海419论坛：Science paper by Toronto lab retracted

A 2014 paper in Science by a lab in Toronto has been retracted after a December expression of concern raised “potential data integrity issues.”爱上海419论坛

The paper, “Mitosis Inhibits DNA Double-Strand Break Repair to Guard Against Telomere Fusions,” is from the lab of Daniel Durocher, a professor of molecular genetics at the University of Toronto.

The retraction notice, published today and signed by all of the original authors, reads, in part:

The article has been cited 258 times, according to Clarivate’s Web of Science. As we previously reported, the two papers are among several from Durocher’s lab that have been flagged for potentially duplicated images.

Meagan Phelan, a communications director for Science, said in an email Durocher and his colleagues are still evaluating the paper in cooperation with the Sinai Health Lunenfeld-Tanenbaum Research Institute. “However, because of the scope and seriousness of the data and image irregularities as they’ve already uncovered them, the authors have decided to retract the paper now, which we commend them for and agree with,” she told us.

Sholto David, who uses the name “Mycosphaerella arachidis” on PubPeer, flagged the potential image duplication in a November 2024 comment上海品茶网. He called the bands in the images “surprisingly similar.”爱上海419

As we reported in early December, the 2014 paper was one of two in Science that received an expression of concern上海新茶工作室微信. A 2007 article, “Orchestration of the DNA-Damage Response by the RNF8 Ubiquitin Ligase,” had a “duplicate image in Fig. 3D,” according to the notice上海品茶工作室. That paper has been cited over 700 times, according to Web of Science.

Phelan told us the journal was “working with the authors to get the experiment reproduced” before considering retraction.

Durocher did not respond directly to our request for comment上海花千坊. After we reached out to him, Jovana Drinjakovic, a scientific communications officer for the Sinai Health Lunenfeld-Tanenbaum Research Institute, sent us the same email we received in December after the two papers received expressions of concern:

Durocher replied on PubPeer threads for both the 2007 paper and the 2014 paper that his lab would look into the irregularities.

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